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KMID : 0361020160590030233
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Korean Journal of Otolaryngology - Head and Neck Surgery
2016 Volume.59 No. 3 p.233 ~ p.237
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A Case of Metachronous Human Papilloma Virus-Associated Squamous Cell Carcinomas in Head and Neck
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김병길:Kim Byung-Kil
이길준:Lee Gil-Joon/김보영:Kim Bo-Young/정만기:Chung Man-Ki
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Abstract
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Synchronous or metachronous head and neck cancer is known to occur in up to 20% of patients, negatively affecting long-term prognosis. We experienced a case of metachronous head and neck cancers in a Human papillomavirus (HPV)-positive patient without a history of smoking, initially presenting with as a cancer of unknown primary (CUP), and then with a contralateral tonsil cancer with metastatic lymphadenopathy five years later. This report highlights the clinical usefulness of HPV typing to determine the optimal extent of surgery and the follow-up strategy in CUP.
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KEYWORD
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Cancer of unknown primary, Human papillomavirus, Metachronous cancer, Surgery, Tonsil cancer
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